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Share It can be predicted with a precision of 75-80% if the delivery will be premature with a blood sample

Lola Rovati @Lolarovati

Every year 15 million premature babies are born in the world, and about a million of them can not survive. According to data from the Spanish Society of Neonatology, premature births in our country have increased by 36% in the last 20 years, and although thanks to increasingly premature medical and scientific advances go forward, there is still a way to go.

A team of scientists led by researchers from Stanford University has developed a test that allows knowing if the delivery will take place before term only with a sample of blood from the mother . The accuracy of the new blood test is between 75 and 80 percent .

According to Mads Melbye, co-author of this research published in the journal Science

"We have identified a group of genes that are highly predictive when it comes to identifying which women are at risk of premature birth.The truth is that I have been trying to understand premature births for many years, and this is the first real breakthrough. scientifically significant that is achieved in a long time. "

Genes that announce prematurity

To carry out the research, they took blood samples from 31 Danish women who were given a blood sample every week throughout their pregnancy. After identifying nine extracellular RNAs (ribonucleic acid) produced by the placenta they created a statistical model that allowed them to predict the gestational age of the baby with an accuracy of 45 percent (in ultrasound it is 48%, but it is a more expensive system). They also found new information about fetal growth. None of these women gave birth prematurely.

Later, they analyzed blood samples taken during the second or third trimester of pregnancy to 38 American women at risk of premature birth, either by having had previous preterm births or early contractions. Of them, 13 gave birth before term.

By analyzing samples from the latter, they identified the extracellular RNA levels of seven genes from the mother and the placenta that can predict which pregnancies will end in a preterm delivery with an accuracy of 75-80%.

Although the sample of women is still very small and is in its early stages, research opens the door to find the biological mechanisms behind premature births and to avoid them, even develop drugs that help delay them.

Via | ScienceEn Magazine and more | New scientific findings could prevent a large percentage of premature births in the future, born between weeks 34 and 36: main problems faced by late preterm infants